ABSTRACT
Antibiotic susceptibility pattern in cases of acute gonococcal urethritis, was studied by single disc diffusion technique and minimum inhibitory concentration (MIC) by agar dilution technique were determined for 5 antibiotics, viz penicillin, ampicillin, tetracycline, gentamicin and norfloxacin. All the penicillinase producing Neisseria gonorrhoeae (PPNG) and non-PPNG strains were sensitive to norfloxacin. 72% of the isolates belonged to serogroup WII/WIII by co-agglutination technique.
Subject(s)
Adult , Agglutination Tests/methods , Antibodies/therapeutic use , Antibodies, Monoclonal/diagnosis , Gonorrhea/drug therapy , Humans , Male , Microbial Sensitivity Tests , Neisseria gonorrhoeae/classification , Porins/immunology , Serotyping/methodsABSTRACT
Sixty patients with Helicobacter Pylori positive non ulcer dyspepsia were randomly allocated to one of the following treatment groups: Group I--norfloxacin 400 mg bid for 10 days, Group II--amoxycillin 500 mg bid plus tinidazole 500 mg bid for 15 days, Group III--colloidal bismuth subcitrate (CBS) 240 mg bid for 4 weeks. H pylori elimination was achieved in 14%, 81%, and 62% in Groups I, II and III respectively. Eradication of H pylori was not observed in Groups I and II, but was achieved in 25% of patients in Group III. Antral gastritis improved in 69% in Group II and 50% in Group III. We conclude that norfloxacin is not effective in H pylori infection. A combination of amoxycillin and tinidazole is highly effective in H pylori elimination with improvement in associated gastritis, but H pylori eradication is not observed with this therapy. CBS is also effective in H pylori elimination though H pylori eradication is achieved in only 25%.
Subject(s)
Adult , Amoxicillin/therapeutic use , Antacids/therapeutic use , Anti-Bacterial Agents/therapeutic use , Anti-Ulcer Agents/therapeutic use , Drug Therapy, Combination , Gastritis/drug therapy , Helicobacter Infections/drug therapy , Helicobacter pylori/drug effects , Humans , Norfloxacin/therapeutic use , Organometallic Compounds/therapeutic use , Tinidazole/therapeutic useABSTRACT
A total of 156 strains of Salmonella isolated at T.N. Medical College and B.Y.L. Nair Ch. Hospital, Bombay over a period of 5 years from 1983 to 1987 were subjected to Phage Typing. Out of the 111 Salmonella typhi strains, phage type A was found in highest proportion (45.95%), followed by phage type E1 (15.32%), 0(9.91%), Deg. Vi. (9.91%) and C5(5.41%). Salmonella paratyphi A had phage type pattern of 1(60.0%), 2(22.86%) and Untypable (14.29%). Majority of the Salmonella typhimurium isolates (90.0%) were untypable.
Subject(s)
Bacteriophage Typing , Humans , India , Salmonella/classification , Salmonella Infections/microbiology , Salmonella PhagesABSTRACT
There was an increase in incidence of meningitis in children within the last three years at the Bai Yamunabai Laxman Rao Nair Charitable Hospital in Bombay. Out of 270 purulent samples, 60 (22.22 percent) were culture positive. Neisseria meningitidis showed an increase from one case in 1985 to 11 cases by the end of 1987. Staphylococcus aureus was isolated from 6 percent cases, Streptococcus pneumoniae 15 percent, and Gram negative bacilli were predominant, isolation rate being 57 percent. Salmonella species were isolated from 6 (10 percent) cases. They were multidrug resistant type, some belonging to the rare zoonotic species.